Tiamulin Fumarate/ Tiamulin Hydrogen Fumarate CAS 55297-96-6

Tiamulin fumarateProperties: This product is white or off-white crystalline powder, soluble in methanol and ethanol, soluble in water, melting point is 143-149 °C.Molecular formula: C28H47NO4S · C4H4O4, molecular weight of 609.8. The content of this product shall not be less than 98.0% according to the anhydrate.

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Tiamulin fumarate

Properties: 
This product is white or off-white crystalline powder, soluble in methanol and ethanol, soluble in water, melting point is 143-149 °C.

Molecular formula: C28H47NO4S · C4H4O4, molecular weight of 609.8. The content of this product shall not be less than 98.0% according to the anhydrate.

Function characteristics:

1. Strong bactericidal power: It has a powerful killing effect on Mycoplasma pneumoniae causing porcine respiratory diseases, Lawsonia causing ileitis, and Spirulina echinococcosis; it can effectively kill Mycoplasma sinensis and slippery chicken causing chicken mycoplasmosis Mycoplasma.

2, the drug effect is remarkable: the animal can reach the highest concentration in the blood medicine 2 hours after feeding tiamulin and maintain for 24 hours, so that the diseased poultry can resume production performance as soon as possible.

3, high safety: no residue in the animal body, no pollution to the environment.

4, low resistance: This product is a semi-synthetic biguanide antibiotic, and there is no similarity with other antibiotics, so there is no cross-resistance problem.

5. Significant economic benefits: This product has a growth-promoting effect on livestock and poultry, increasing the rate of return on feed, early pigs slaughtering time, increasing laying rate of laying hens, and promoting broiler weight gain.

Indications:

1. For the pig industry: tiamulin is used for the prevention and treatment of diseases caused by mycoplasma infection and Escherichia coli, Salmonella, spirochetes, etc., for Mycoplasma pneumoniae, Haemophilus pleuropneumonia, Endemic pneumonia (gasposis) ) and pig dysentery have special effects. At the same time, it has a good effect on mycoplasmal arthritis, anti-line pleural pneumonia, ileitis, colitis, edema and other diseases.

2. Applied to chicken industry: The loss of mycoplasma to the chicken industry is mainly due to reduced egg production, lower hatching rate, increased mortality of chickens and reduced weight gain. The key to controlling mycoplasmosis is to prevent the spread of pathogens through breeders. This product can effectively control Mycoplasma gallisepticum and Mycoplasma synoviae.

Dosage: 

1, for pigs: prevention: 50ppm in the high-incidence period, 5-7 days in a row; treatment: 100ppm for 7-10 days.

2, applied to chicken: Prevention: 125ppm drinking water, 3 days a month to the peak of egg production, the mixture doubled. Treatment: 250ppm drinking water, used for 3-5 days, then halved for 5 days.

Precautions:

1 Avoid contact with eyes and skin.

2 Prohibition of mixing with polyether antibiotics such as monensin and salinomycin; and antibiotics that bind to the 50S subunit of bacterial ribosomes (such as clindamycin, lincomycin, erythromycin, tylosin) Etc.), used together, resulting in reduced efficiency due to competitive sites.

3 It is synergistic with tetracyclines (oxytetracycline, chlortetracycline, doxycycline), colistin sulfate, amoxicillin, aminoglycosides, peptides, sulfonamides, nitrofurans, etc.

4 The drug holiday is 5 days.

Tiamulin Fumarate/ Tiamulin Hydrogen Fumarate CAS 55297-96-6

Appearance

White or almost white crystalline powder

Assay

98.8.0-102%min

Specific rotation

+25°C

PH VALUE

3.1-4.1

fumarate

83.5MG-87.3MG

Loss on Drying  

0.3%

Absorbace

650nm:0.03max

400nm:0.15max

Heavy Metal

≤0.001%

Chromatographic purity

conforms

Residue on ignition

0.1%MAX

Melting point

143-149 °C

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