Supply Pharmaceutical Powder Cas 616202-92-7 Hight Purity Lorcaserin
Hydrochloride Powder
Description:
Lorcaserin hcl is an FDA-approved prescription weight-loss medication that, when used
with diet and exercise, can help some overweight† adults with a weight-related medical problem,
or obese adults, lose weight and keep it off. It is not known if Lorcaserin hcl when taken with
other prescription, over-the-counter, or herbal weight-loss products is safe and effective. It is
not known if Lorcaserin hcl changes your risk of heart problems, stroke, or death due to heart
problems or stroke.
Functions:
Lorcaserin is a selective 5-HT2C receptor agonist, and in vitro testing of the drug showed
reasonable selectivity for 5-HT2C over other related targets. 5-HT2C receptors are located
almost exclusively in the brain, and can be found in the choroid plexus, cortex, hippocampus,
cerebellum, amygdala, thalamus, andhypothalamus. The activation of 5-HT2C receptors in the
hypothalamus is supposed to activate proopiomelanocortin(POMC) production and consequently
promote weight loss through satiety. This hypothesis is supported by clinical trials and other
studies. While it is generally thought that 5-HT2C receptors help to regulate appetite as well
as mood, and endocrine secretion, the exact mechanism of appetite regulation is not yet known.
Lorcaserin has shown 100x selectivity for 5-HT2C versus the closely related 5-HT2B receptor.
Hydrochloride Powder
Product Name | Lorcaserin |
Specification | >99% |
Test Method | HPLC |
Molecular Formula | C11H14ClN/C11H15Cl2N |
EINECS No. | - |
Description:
Lorcaserin hcl is an FDA-approved prescription weight-loss medication that, when used
with diet and exercise, can help some overweight† adults with a weight-related medical problem,
or obese adults, lose weight and keep it off. It is not known if Lorcaserin hcl when taken with
other prescription, over-the-counter, or herbal weight-loss products is safe and effective. It is
not known if Lorcaserin hcl changes your risk of heart problems, stroke, or death due to heart
problems or stroke.
Functions:
Lorcaserin is a selective 5-HT2C receptor agonist, and in vitro testing of the drug showed
reasonable selectivity for 5-HT2C over other related targets. 5-HT2C receptors are located
almost exclusively in the brain, and can be found in the choroid plexus, cortex, hippocampus,
cerebellum, amygdala, thalamus, andhypothalamus. The activation of 5-HT2C receptors in the
hypothalamus is supposed to activate proopiomelanocortin(POMC) production and consequently
promote weight loss through satiety. This hypothesis is supported by clinical trials and other
studies. While it is generally thought that 5-HT2C receptors help to regulate appetite as well
as mood, and endocrine secretion, the exact mechanism of appetite regulation is not yet known.
Lorcaserin has shown 100x selectivity for 5-HT2C versus the closely related 5-HT2B receptor.