CAS No. :64485 -93-4
Molecular formula: C16H16N5NaO7S2
Molecular Weight: 477.45
Refractive index: 61 °(C = 1, H2O)
Storage conditions :2-8 °C
Properties: white to yellowish white crystals; odorless or slight special smell
Application:Patients are susceptible to various infections, such as respiratory, facial, abdominal, biliary tract, meningitis, gonorrhea, urinary tract infections, septicemia.
The main clinical infection for susceptible strains of meningitis, pneumonia, skin and soft tissue infections, peritonitis, urinary tract infections, gonorrhea, liver and gallbladder infection, surgical trauma, sepsis, and genital infections. As a treatment for gonorrhea has been first-line drugs.
Cefotaxime sodium is a third-generation semi-synthetic cephalosporin. It is not as effective against Gram-positive bacteria as cefazolin. Enterococcus is resistant to this product. It is not effective against penicillin-resistant pneumococci. It has a strong effect on Gram-negative bacteria. Bactericidal activity, antibacterial effect against Escherichia coli, influenza bacillus, Klebsiella pneumoniae, Proteus mirabilis, Salmonella is stronger than cefoperazone, weak or resistant to Bacteroides fragilis, Pseudomonas aeruginosa, Enterobacter cloacae Product is not sensitive.
Cefotaxime is widely distributed in various tissues and body fluids throughout the body. The concentration of the drug in normal cerebrospinal fluid is very low; after application of this product in meningitis patients, the effective concentration can be reached in the cerebrospinal fluid. Bronchial secretions, middle ear discharge, pleural effusion, empyema, ascites, gallbladder wall, bile, bone tissue can also reach effective concentration: this product can enter the fetal blood circulation through the placental barrier, a small amount can also Enter the milk.
Cefotaxime sodium is used for infection of respiratory tract, urinary tract, bones and joints, skin and soft tissues, abdominal cavity, biliary tract, digestive tract, facial features, genitals, etc. caused by sensitive bacteria, infection caused by burns and trauma, and sepsis, central The infection is also effective.